July 18, 2018The Journal of Infectious DiseasesOpen Access

Torque Teno Virus as a Novel Biomarker Targeting the Efficacy of Immunosuppression After Lung Transplantation

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Why the study?

Does Torque teno virus (TTV) load predict clinical events and efficacy of immunosuppression in lung transplant recipients?

Population

143 lung transplant recipients (LTRs)

Design

Cohort

Authors

PJPéter JakschBarmherzige Schwestern Krankenhaus Wien MKMichael KundiMedical University of Vienna IGIrene GörzerMedical University of Vienna

Discussion

Member takes

Implication

May inform IS monitoring in LTRs; leaves open validation for infections, CLAD, and survival.

Structured PICO

Does Torque teno virus (TTV) load predict clinical events and efficacy of immunosuppression in lung transplant recipients?

Population

143 lung transplant recipients (LTRs)

Intervention

Torque teno virus (TTV) load monitoring by quantitative TTV-DNA PCR

Outcome

Occurrence of severe infections, chronic lung allograft dysfunction (CLAD), acute cellular rejection (ACR), and deathsurrogate

TTV-load predicts clinical events such as severe infections and chronic lung allograft dysfunction, suggesting its potential utility in optimizing immunosuppression after lung transplantation.

Cite This Study

Jaksch et al. (2018) studied this question.

synapsesocial.com/papers/6a6fb0a1fe4101aa97dfde02 https://doi.org/10.1093/infdis/jiy452

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Torque Teno Virus as a Novel Biomarker Targeting the Efficacy of Immunosuppression After Lung Transplantation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Torque Teno Virus as a Novel Biomarker Targeting the Efficacy of Immunosuppression After Lung Transplantation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider