Why the study?
Does a 12-hour observation period safely exclude acute myocardial infarction in low-risk patients admitted with acute chest pain?
Does a 12-hour observation period safely exclude acute myocardial infarction in low-risk patients admitted with acute chest pain?
A 12-hour observation period is sufficient to safely rule out acute myocardial infarction in patients presenting with acute chest pain who have a low initial clinical probability and no recurrent pain or enzyme abnormalities in the first 12 hours.
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May support safe 12-hour rule-out in low-risk chest pain; leaves open randomized confirmation before practice change.
Lee et al. (1991) studied this question.
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