January 1, 1985Circulation
The long QT syndrome: a prospective international study.
Why the study?
Do left stellate ganglionectomy and beta-blocker therapy reduce cardiac events in patients with idiopathic long QT syndrome?
Population
196 patients with idiopathic long QT syndrome, mean age 24 years, 64% female, multinational.
Design
Cohort
Follow-up
average 26 months
Authors
Discussion
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Member takes
Implication
Beta-blockers and left stellate ganglionectomy were associated with fewer events in LQTS; hypothesis-generating and requires prospective confirmation.
Structured PICO
Do left stellate ganglionectomy and beta-blocker therapy reduce cardiac events in patients with idiopathic long QT syndrome?
P
Population
196 patients with idiopathic long QT syndrome, mean age 24 years, 64% female, multinational.
I
Intervention
Left stellate ganglionectomy and beta-blocker therapy
O
Outcome
Postenrollment syncope or sudden deathhard clinical
This prospective international study identified key risk factors for syncope and sudden death in long QT syndrome and demonstrated the protective effects of beta-blockers and left stellate ganglionectomy.
Cite This Study
Moss et al. (1985) studied this question.