August 1, 1986Circulation ResearchOpen Access

Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog.

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Why the study?

Does power spectral analysis of heart rate and arterial pressure variability reflect sympatho-vagal interaction in humans and dogs?

Population

57 normal human subjects, 7 additional subjects for invasive arterial pressure recording, and a group of…

Comparison

Physiological maneuvers, pharmacological… vs Baseline resting/recumbent conditions.

Design

Other

Authors

MPM. PaganiCentro Universitário Cesumar FLFederico LombardiUniversity of Foggia SGStefano GuzzettiHeart Failure & Transplant

Discussion

Member takes

Implication

Supports spectral HRV analysis as sympatho-vagal marker; leaves open clinical adoption pending prospective validation.

Structured PICO

Does power spectral analysis of heart rate and arterial pressure variability reflect sympatho-vagal interaction in humans and dogs?

Population

57 normal human subjects (age 20-60 years), 7 additional subjects for invasive arterial pressure recording, and a group of conscious dogs.

Intervention

Physiological maneuvers (90 degrees upright tilt, controlled respiration), pharmacological interventions (acute IV propranolol 0.2 mg/kg, chronic oral propranolol 0.6 mg/kg t.i.d., IV nitroglycerin), and bilateral stellectomy (in dogs).

Comparator

Baseline resting/recumbent conditions.

Outcome

Power spectral density of R-R interval and arterial pressure variabilities (low frequency, high frequency components, and LF:HF ratio).surrogate

Power spectral analysis of heart rate and arterial pressure variabilities provides a quantitative marker of sympatho-vagal interaction, with the low-frequency component reflecting sympathetic activity and the high-frequency component reflecting vagal tone.

Cite This Study

Pagani et al. (1986) studied this question.

synapsesocial.com/papers/69f69177e405cc4465bc2b96 https://doi.org/10.1161/01.res.59.2.178

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Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider