Nevus lipomatosus cutaneous superficialis presenting as a coalescent gluteal plaque.

Nevus lipomatosus cutaneous superficialis (NLCS) is a rare benign cutaneous hamartoma characterised by the presence of mature adipose tissue within the dermis. We report the case of a woman in her mid-20s who presented with an uncomfortable progressively enlarging lesion over the gluteal region. Histopathological examination of a skin biopsy demonstrated mature adipocytes interspersed among dermal collagen bundles, confirming the diagnosis. The patient underwent surgical excision for symptomatic relief, with no recurrence at one-year follow-up. This case underscores the importance of clinicopathological correlation in differentiating NLCS from other dermal and subcutaneous nodular lesions.