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May 3, 2026

Severe dengue fever with life-threatening gastrointestinal hemorrhage in a liver transplant recipient undergoing adjuvant chemotherapy for hepatocellular carcinoma.

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Authors

JFJihua FengGuangxi Medical UniversityXZXiaoling ZhuGuangxi Medical UniversityXZXiaowen ZhengGuangxi Medical University

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Implication

Randomized trial reveals life-threatening gastrointestinal hemorrhage in a liver transplant recipient, suggesting the need for careful management.

Key Points

  • To highlight the complications of severe dengue in immunocompromised patients undergoing treatment for liver cancer.
  • Case report of a liver transplant recipient
  • Concurrent adjuvant chemotherapy with oxaliplatin and fluorouracil
  • Diagnosis via dengue virus RNA testing and intensive care management.
  • Life-threatening grade 3 bone marrow suppression with severe anemia and gastrointestinal hemorrhage observed.
  • Acute kidney injury necessitated intensive care management and multidisciplinary support.
  • Successful management involved balancing immunosuppressive therapy adjustments and supportive care interventions.

Cite This Study

Feng et al. (2026) studied this question.

synapsesocial.com/papers/69f6e6648071d4f1bdfc7058https://doi.org/10.1186/s12879-026-13479-0
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Also Consider

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