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May 11, 2019Critical Reviews in Clinical Laboratory Sciences

Growth differentiation factor 15: A novel biomarker with high clinical potential

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Authors

SDStéphanie DesmedtVDValérie DesmedtLVLeen De Vos

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Overview

Review explores GDF-15's role as a biomarker for various diseases, suggesting it may predict health outcomes.

Key Points

  • This review aims to assess GDF-15's potential as a clinical biomarker for multiple diseases.
  • Review of current clinical data on GDF-15 as a biomarker
  • Focus on cardiovascular disease, kidney disease, liver disease, metabolic syndrome, diabetes, and sepsis.
  • Analysis of serum GDF-15 concentrations and their implications for health outcomes.
  • GDF-15 levels correlate with systemic responses and predictive of all-cause mortality.
  • Strong association with inflammatory processes involved in chronic diseases.
  • Emerging evidence supporting its role in metabolic regulation and tissue repair.

Cite This Study

Desmedt et al. (2019) studied this question.

synapsesocial.com/papers/69f7e2dfb3779c469228903ehttps://doi.org/10.1080/10408363.2019.1615034
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