Population
13 anesthetized open-chest dogs (anterior-apical group, n=7; posterior-basal group, n=6)
Comparison
Three levels of coronary inflow restriction… vs Different levels of ischemia and different…
Design
Preclinical
Authors
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Requires caution interpreting epicardial shortening during ischemia; leaves open validation of transmural metrics in humans.
Epicardial segment shortening underestimates transmural dysfunction during non-transmural ischemia, with significant regional variability in the epicardial response.
Gallagher et al. (1985) studied this question.
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