Noninvasive Diagnosis of Ischemia-Induced Wall Motion Abnormalities With the Use of High-Dose Dobutamine Stress MRI
Why the study?
Does dobutamine stress magnetic resonance improve diagnostic accuracy for detecting significant coronary artery disease compared to dobutamine stress echocardiography in patients with suspected coronary artery disease?
Population
208 consecutive patients (147 men, 61 women) with suspected coronary artery disease
Comparison
Dobutamine stress magnetic resonance using a… vs Dobutamine stress echocardiography with harmonic…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
DSMR may improve CAD detection over DSE; leaves open prospective outcome trials before practice change.
Structured PICO
Does dobutamine stress magnetic resonance improve diagnostic accuracy for detecting significant coronary artery disease compared to dobutamine stress echocardiography in patients with suspected coronary artery disease?
P
Population
208 consecutive patients (147 men, 61 women) with suspected coronary artery disease
I
Intervention
Dobutamine stress magnetic resonance (DSMR) (1.5 T) using a standard dobutamine-atropine scheme
C
Comparator
Dobutamine stress echocardiography (DSE) with harmonic imaging
O
Outcome
Diagnostic accuracy (sensitivity and specificity) for detecting significant coronary heart disease (≥50% diameter stenosis on cardiac catheterization)surrogate
High-dose dobutamine stress MRI provides significantly higher diagnostic accuracy than dobutamine stress echocardiography for detecting significant coronary artery disease.
Limitations
- 18 patients could not be examined by DSMR due to claustrophobia or adipositas
- 18 patients could not be examined by DSE due to poor image quality
Cite This Study
Nagel et al. (1999) studied this question.