December 2, 1998JAMA
Abdominal Adiposity and Coronary Heart Disease in Women
Why the study?
Do higher waist-hip ratio and waist circumference increase the risk of incident coronary heart disease in women?
Population
44,702 US female registered nurses aged 40 to 65 years, free of prior CHD, stroke, or cancer in 1986.
Comparison
Higher waist-hip ratio and greater waist… vs Lower waist-hip ratio and lower waist…
Design
Cohort
Follow-up
8 years
Authors
Discussion
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Member takes
Implication
May inform CHD risk stratification beyond BMI in women; extends observational data but remains hypothesis-generating.
Structured PICO
Do higher waist-hip ratio and waist circumference increase the risk of incident coronary heart disease in women?
P
Population
44,702 US female registered nurses aged 40 to 65 years, free of prior CHD, stroke, or cancer in 1986.
I
Intervention
Higher waist-hip ratio (WHR ≥0.88) and greater waist circumference (≥96.5 cm)
C
Comparator
Lower waist-hip ratio (WHR <0.72) and lower waist circumference
O
Outcome
Incidence of CHD (nonfatal myocardial infarction or CHD death)hard clinical
Abdominal adiposity, measured by waist-hip ratio or waist circumference, is a strong independent risk factor for coronary heart disease in women, even among those with a normal BMI.
Cite This Study
Kathryn M. Rexrode (1998) studied this question.