November 1, 1981Circulation ResearchOpen Access

Electrotonically mediated delayed conduction and reentry in relation to "slow responses" in mammalian ventricular conducting tissue.

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Structured PICO

Population

Isolated mammalian ventricular false tendon preparations

Intervention

Perfusion of a central compartment with isotonic sucrose or 'ischemic' solution to create a narrow zone of block, with or without verapamil

Comparator

Comparison between sucrose gap and ischemic gap models, and presence vs absence of verapamil

Outcome

Mechanism of delayed conduction and occurrence of reflected reentrysurrogate

Very slow conduction and reentry in ischemic ventricular tissue may be mediated by electrotonic transmission across inexcitable segments rather than uniform slow conduction.

Discussion

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Implication

Supports electrotonic reentry in ischemic gaps; hypothesis-generating for human ventricular arrhythmia mechanisms.

Cite This Study

Antzelevitch et al. (1981) studied this question.

synapsesocial.com/papers/69f7e3ee6d1e8212df5a2ef2 https://doi.org/10.1161/01.res.49.5.1129

View Full Paper

Ask AI

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Electrotonically mediated delayed conduction and reentry in relation to "slow responses" in mammalian ventricular conducting tissue.

Structured PICO

Discussion

Implication

Cite This Study

Electrotonically mediated delayed conduction and reentry in relation to "slow responses" in mammalian ventricular conducting tissue.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider