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May 4, 2026Frontiers in MedicineOpen Access

Advances and future perspectives of kidney organoid technology in renal disease research and clinical translation

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Authors

ZZZichun ZhaoFirst Hospital of China Medical UniversityKTKuan TongFirst Hospital of China Medical UniversityKDKunfei DengFirst Hospital of China Medical University

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Implication

Review highlights advances in kidney organoids for disease mechanisms, treatment, and challenges in translation.

Key Points

  • The review aims to explore current technologies and applications of kidney organoid models in renal disease research and their clinical translations.
  • Comprehensive review of kidney organoid technologies and applications.
  • Focus on recent advances in vascularization, bioprinting, and microenvironment simulation.
  • Discussion on translation challenges such as production scale and ethical considerations.
  • Kidney organoids effectively model renal diseases, aiding drug screening and therapeutic evaluations.
  • Emerging trends show integration of organoids with precision medicine and advanced biotechnologies.
  • Challenges include achieving data reproducibility and addressing ethical and regulatory issues.

Cite This Study

Zhao et al. (2026) studied this question.

synapsesocial.com/papers/69f836aa3ed186a739980e59https://doi.org/10.3389/fmed.2026.1815902
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