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May 4, 2026Medicina3 citationsOpen Access

Risk Factors Associated with Complications and Early Mortality of Hip Fracture Surgery in Elderly Patients

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PMPovilas MasionisGVGiedrius VaitukaitisAMAgnietė Masionienė

Key Result

Any complication increased the risk of 30-day mortality by 5.6 times (95% CI 1.6-19.9, p=0.008) in elderly patients undergoing hip fracture surgery.

Key Points

  • This study evaluates risk factors for early complications and 30-day mortality in elderly patients with hip fractures.
  • Prospective study with 583 patients aged over 65 who sustained hip fractures and underwent surgery.
  • 30-day follow-up for recording complications and mortality.
  • Regression models used to analyze patient characteristics and laboratory markers.
  • Complications increased mortality risk by 5.6 times (95% CI 1.6–19.9, p = 0.008).
  • More than 6 comorbidities raised mortality risk by 8.2 (95% CI 1.9–35.5, p = 0.005).
  • Age > 85 years led to a 2.2-fold increase in mortality risk (95% CI 1.2–4.1, p = 0.015).

Study Design

Type

Cohort (n=583)

Structured PICO

What are the risk factors associated with 30-day mortality and early complications in elderly patients undergoing hip fracture surgery?

P
Population
583 patients over 65 years old who sustained hip fractures from fall and underwent surgery
I
Intervention
Evaluation of risk factors including patient characteristics, comorbidities, Vitamin D, and NT-proBNP levels
O
Outcome
30-day mortality and early complicationshard clinical

Age >85, having >6 comorbidities, Vitamin D levels, and NT-proBNP >780 ng/L are significant predictors of 30-day mortality and complications following hip fracture surgery in the elderly.

Main Result

Effect estimate: OR 5.6 (95% CI 1.6-19.9)

p-value: p=0.008

Abstract

Background and Objectives: High rates of mortality and morbidity among elderly hip fracture patients are a recognized global issue. This study aimed to evaluate risk factors for early complications and 30-day mortality in hip fracture patients. Materials and Methods: The prospective study included 583 patients over 65 years old who sustained hip fractures from fall and underwent surgery. Each patient was followed up for 30 days and complications were recorded. Regression models were used to assess the influence of patient characteristics and laboratory markers on 30-day mortality and complications. Results: Any complication increased the risk of mortality by 5.6 times (95% CI 1.6–19.9, p = 0.008). Having > 6 comorbidities increased the risk of mortality by 8.2 (95% CI 1.9–35.5, p = 0.005) and the risk of complications by 2.3 (95% CI 1.9–35.5, p = 0.000). Patients > 85 years old had increased risk of mortality by 2.2 times (95% CI 1.2–4.1, p = 0.015) and a 1.7-fold increase in risk of complications (95% CI 1.2–2.4, p = 0.005). Vitamin D significantly predicted mortality with odds ratio of 2.1 (95% CI 1.1–4.1, p = 0.028). Serum N-terminal pro-brain natriuretic peptide levels > 780 ng/L predicted 2.3-fold increase in mortality (95% CI 1.0–4.9, p = 0.040) and a 2.6-fold risk of complications (95% CI 1.7–3.9, p = 0.000). Conclusions: Occurrence of complication increases the risk of mortality. Age and comorbidities are significant factors associated with 30-day mortality and complications. Vitamin D levels are associated with higher risk of mortality. N-terminal pro-brain natriuretic peptide levels correspond to higher risks of death and complications.

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Cite This Study

Masionis et al. (2026) conducted a cohort in hip fracture (n=583). Risk factors (complications, comorbidities, age, Vitamin D, NT-proBNP) was evaluated on 30-day mortality (OR 5.6, 95% CI 1.6-19.9, p=0.008). Any complication increased the risk of 30-day mortality by 5.6 times (95% CI 1.6-19.9, p=0.008) in elderly patients undergoing hip fracture surgery.

synapsesocial.com/papers/69f837003ed186a739981246https://doi.org/10.3390/medicina62050825
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