Key result
In elderly patients undergoing hip fracture surgery, the mortality rate was 15.6%, with independent risk factors including advanced age, male gender, rural living, and preoperative delay >7 days.
Observational (n=480)
Multiple patient and perioperative factors, including advanced age, male gender, preoperative delay, and specific laboratory abnormalities, independently predict mortality and poor functional outcomes in elderly patients after hip fracture surgery.
May inform perioperative risk stratification in elderly hip fracture patients; leaves open whether targeting identified factors improves survival.
This study aimed to evaluate the functional outcomes and mortality following hip fracture surgery in elderly patients, and to identify the associated risk factors. Between January 2016 and December 2017, 480 consecutive patients were finally included for data analyses. The Harris score and Barthel index were used to evaluate the hip function and ability to perform activities of daily living (ADL). Univariate and multivariate logistics regression analyses were performed to determine the independent risk factors for mortality, poor hip function or poor ability to perform ADL. The mortality rate was 15.6% (75/480). In the survivors, poor outcome developed in 133 (32.8%) patients and poor ADL was in 72 (17.8%) patients. The independent factors that influenced mortality were advanced age (p = 0.033), male gender (0.031), living in rural area (p < 0.001), self-reported diabetes (p = 0.005), tumor (p = 0.024), preoperative delay >7 days (p = 0.020), postoperative drainage use (p = 0.034), WBC > 10 × 109/L (p = 0.005), reduced RBC (p = 0.011), PLT < 100 × 109/L (p < 0.001), ALB < 35 g/L (p < 0.001) and CK > 200 U/L (p = 0.003). The independent factors that influenced the hip function were male gender (p = 0.009), WBC > 10 × 109/L (p < 0.001), lower HBG (p = 0.005), and ALB < 35 g/L (p < 0.001). The independent factors that influenced the ability to perform ADL were diagnosis of trochanteric fracture (p = 0.048), preoperative delay > 7 days (p = 0.027), postoperative drainage use (p = 0.010), elevated WBC (p = 0.020), lower HGB (p < 0.001), PLT < 100 × 109/L (p = 0.002), and ALB < 35 g/L (p < 0.001). Although most of risk factors were not modifiable, they aid in patient individual risk evaluation, risk stratification, and counseling patients or relatives.
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Meng et al. (2019) conducted an observational in Elderly hip fractures (n=480). Patient and perioperative risk factors was evaluated on Mortality, poor hip function, and poor ability to perform ADL. In elderly patients undergoing hip fracture surgery, the mortality rate was 15.6%, with independent risk factors including advanced age, male gender, rural living, and preoperative delay >7 days.
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