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This study aims to compare the surgical outcomes of grade 2 lumbar spondylolisthesis between patients under and over 65 years of age.

May 4, 2026

Does surgical treatment of grade 2 spondylolisthesis have sustained improvement in postoperative outcomes regardless of age? A Spine CORe™ analysis of QOD data.

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This study aims to compare the surgical outcomes of grade 2 lumbar spondylolisthesis between patients under and over 65 years of age.
Retrospective analysis of the Quality Outcomes Database for patients who underwent arthrodesis for grade 2 lumbar spondylolisthesis.
328 patients identified with 81% follow-up across 14 sites, compared outcomes between age groups using Wilcoxon rank-sum tests.
Evaluated outcomes included NRS back pain, NRS leg pain, Oswestry Disability Index, EQ-5D scores, and patient satisfaction at multiple time points.
EQ-5D and ODI scores significantly improved postoperatively in both age groups (p < 0.001).
No significant differences in ODI or EQ-5D scores between age groups at any time points examined (p > 0.05).
Majority satisfaction: 83.5% younger and 89.5% older patients reported satisfaction after 5 years, with no significant difference in postoperative satisfaction scores across age groups.

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Randomized trial compares surgical outcomes in younger and older patients, suggesting similar benefits regardless of age.

Kharas et al. (2026) studied this question.

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