Key result
Surgical resection of a rare lipomatous hypertrophy of the interatrial septum extending into the superior vena cava successfully resolved the patient's obstructive symptoms.
Why the study?
Lipomatous hypertrophy of the interatrial septum is rare, and extension to surrounding structures is extremely uncommon but may result in obstructive symptoms requiring surgical resection.
Case Report (n=1)
No
Symptomatic lipomatous hypertrophy of the interatrial septum extending into the superior vena cava can be successfully managed with surgical resection and reconstruction, providing complete symptom relief.
Answers are grounded in this paper and cite their sources.
Rare SVC obstruction from lipomatous hypertrophy extension may warrant resection; leaves open incidence and management standards in this entity.
Background: Lipomatous hypertrophy of the interatrial septum is rare, and extension to surrounding structures is extremely uncommon, yet may result in obstructive symptoms requiring surgical resection. Case: This case report describes a 56-year-old male who had been undergoing an outpatient workup for lightheadedness, palpitations, and chest pain. Computed tomography revealed a large mass extending from the superior vena cava to the atrial septum, resulting in compression of the superior vena cava. Magnetic resonance imaging suggested lipomatous characteristics. Subsequently, the patient was referred for cardiac surgery and underwent an uncomplicated resection of the mass and reconstruction of the superior vena cava, with ensuing resolution of the symptoms. Conclusion: Lipomatous hypertrophy of the interatrial septum can rarely expand into the superior vena cava, causing obstructive symptoms. Symptomatic relief may be achieved via resection of the entire mass, which can be performed without violating the atrial septum and atrial wall.
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Smith et al. (2026) conducted a case report in Lipomatous hypertrophy of the interatrial septum with superior vena cava compression (n=1). Surgical resection and reconstruction of the superior vena cava was evaluated on Symptom resolution and relief of superior vena cava obstruction. Surgical resection of a rare lipomatous hypertrophy of the interatrial septum extending into the superior vena cava successfully resolved the patient's obstructive symptoms.
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