Key result
Modern ART linked to ~68% lower mortality in HIV-associated cardiomyopathy.
Why the study?
HIV-associated cardiomyopathy causes significant morbidity and mortality, but its individual-patient clinical spectrum has not been systematically synthesized.
Systematic Review (n=99)
Yes
HIV-associated cardiomyopathy is etiologically heterogeneous, and while mortality has significantly declined in the modern ART era, there is a critical lack of data from high-burden regions like sub-Saharan Africa.
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Reinforces modern ART as essential in HIV-associated cardiomyopathy; confirms care advances while highlighting persistent morbidity and research gaps.
Hozayen et al. (2026) conducted a systematic review in HIV-associated cardiomyopathy (n=99). HIV-associated cardiomyopathy is heterogeneous, with uncontrolled HIV phenotypes predominating (64%) and mortality declining from 65% pre-ART to 21% in the modern ART era.
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