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May 4, 2026

Clinical evaluation of different bi-layer biomimetic strategies of composite resin in large class I cavities: an 18-month randomized clinical trial.

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Authors

MMMohammed Abd El Ghany MohammedTanta UniversityMHMohammed Abdallah HassanTanta UniversityKMKholood El Sayed MorsyTanta University

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Implication

Randomized trial assesses clinical performance of different composite resins in large class I cavities, indicating comparable effectiveness.

Key Points

  • This study aims to evaluate the clinical performance of various biomimetic composite resin strategies in large class I cavities over 18 months.
  • Randomized, double-blind, split-mouth trial with 40 participants aged 35-45 years.
  • Participants received four biomimetic bases: short-fiber composite, long-fiber composite, RMGIC, and flowable composite.
  • Clinical assessments were conducted at baseline, 6, 12, and 18 months for aesthetic, functional, and biological properties.
  • No fractures or secondary caries were reported in the evaluated restorations over 18 months.
  • Statistical analysis revealed no significant differences among the four biomimetic strategies (p > 0.05).
  • All tested biomimetic composite resins demonstrated comparable excellent short-term clinical performance.

Cite This Study

Mohammed et al. (2026) studied this question.

synapsesocial.com/papers/69f837d73ed186a739982163https://doi.org/10.1186/s12903-026-08403-6
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