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Synapse
May 4, 20264 citations

Activated T cell extracellular vesicle DNA transfer enhances antigen presentation and anti-tumor immunity.

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MHMengying HuDLDi-Ao LiuIWInbal Wortzel

Key Points

  • The central aim is to evaluate how activated T cell extracellular vesicle DNA transfer affects antigen presentation and anti-tumor immunity.
  • Evaluation of T cell-derived extracellular vesicles in vitro and in vivo
  • Assessment of antigen presentation enhancement
  • Measurement of anti-tumor immune response
  • Increased antigen presentation observed post DNA transfer
  • Enhanced anti-tumor immune response without significant autoimmunity
  • Potential for therapeutic application in cancer immunotherapy

Abstract

that boosts APP and anti-tumor immunity while limiting autoimmunity.

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Cite This Study

Hu et al. (2026) studied this question.

synapsesocial.com/papers/69f838453ed186a7399826bbhttps://doi.org/10.1016/j.ccell.2026.03.023
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