Are the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and atherogenic index of plasma (AIP) associated with obstructive sleep apnea?
NHHR and AIP are independent risk factors for obstructive sleep apnea and may serve as potential diagnostic tools.
Background: Obstructive sleep apnea (OSA) is a prevalent sleep disorder associated with metabolic, cardiovascular disorders. The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and atherogenic index of plasma (AIP) are thought to be better ways to detect cardiovascular diseases than single lipid parameters. The relationship between NHHR or AIP and OSA remains ambiguous. Methods: . Binary logistic regression analysis was conducted to investigate the association between the NHHR and AIP with OSA. To evaluate the diagnostic performance of the NHHR and AIP for OSA, we conducted receiver operating characteristic (ROC) curve analysis. Results: < 0.001) were independent factors for OSA. The area under the curve (AUC) values for the identifying OSA were 0.730 for the NHHR, 0.658 for the AIP and 0.763 for the combined model, respectively. Conclusions: Our study indicates the NHHR and AIP were independent risk factors for OSA and can be used as potential tools for OSA.
Li et al. (Mon,) studied this question.
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