Why the study?
Guidelines recommend surgery in asymptomatic patients with mitral regurgitation, but ischemic stroke risks after surgery were unknown.
Does surgical correction of mitral regurgitation affect the risk of ischemic stroke in patients with mitral regurgitation compared to the general population?
Does surgical correction of mitral regurgitation affect the risk of ischemic stroke in patients with mitral regurgitation compared to the general population?
While early ischemic stroke risk is high after mitral regurgitation surgery, long-term risk is similar to the general population for patients undergoing valve repair or biological replacement, supporting a preference for valve repair.
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Early IS risk after MR surgery warrants prevention efforts; leaves open optimal long-term antithrombotic strategies pending RCTs.**[[1]](https://www.jacc.org/doi/10.1016/j.jacc.2007.10.
Russo et al. (2008) studied this question.
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