Key result
SCORE2 identifies over twofold more patients with elevated vascular age compared to original SCORE.
Why the study?
Different methods of calculating vascular age can provide different results, and their comparative evaluation is needed to understand these differences.
Do SCORE, SCORE2, and Framingham Risk Score methods yield different vascular age calculations in adults aged 40-65?
Cross-Sectional (n=141)
Yes
Do SCORE, SCORE2, and Framingham Risk Score methods yield different vascular age calculations in adults aged 40-65?
Different cardiovascular risk scoring systems (SCORE, SCORE2, FRS) yield significantly different vascular age estimates, highlighting the need for standardization in risk communication.
Answers are grounded in this paper and cite their sources.
Discrepancies across risk scores warrant cautious interpretation in practice; leaves open need for standardization and validation studies.
Background/objectives: Calculation of vascular age can help patients to understand the importance of adherence to a healthy lifestyle and medications. There are different methods of calculating vascular age, but different methods can provide different vascular age results. Our aim was to evaluate vascular age based on the Systematic Coronary Risk Evaluation (SCORE), Systematic Coronary Risk Evaluation 2 (SCORE 2) and Framingham Risk Score (FRS) methods. Methods: Subjects between the ages of 40–65 were involved. Vascular ages were defined based on SCORE, SCORE2 and FRS methods according to data from the literature. Results: In total, 141 patients were involved in the study; among them 94 had hypertension (HT) and 23 had white-coat hypertension. In the total population, SCORE2 and FRS vascular ages were higher compared to chronological age. SCORE2 and FRS vascular ages were higher than SCORE vascular age, and FRS vascular age was higher compared to SCORE2 as well. These tendencies were the same in the case of hypertensive patients and in patients with white-coat hypertension. In healthy patients, there were no differences between chronological age and vascular age. Conclusions: The differences found between the calculated vascular ages and the proportion of subjects with elevated vascular age warrant further comparison of different vascular age calculation methods.
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Gyöngyösi et al. (2025) conducted a cross-sectional in Hypertension, white-coat hypertension, and healthy subjects (n=141). SCORE2 and FRS vascular age calculation vs. SCORE vascular age calculation was evaluated on Proportion of subjects with elevated vascular age (≥2 years higher than chronological age) (p=<0.05). SCORE2 and FRS methods identified a higher proportion of subjects with elevated vascular age compared to the SCORE method.
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