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Explores enhanced drug release using ultrasound in implantable systems, suggesting effective management for chronic conditions.
ultrasound for 5 min with 9.13° C increase as a safe operating condition. Under the selected setting, ultrasound significantly enhanced drug release for around 9.7-fold by accelerating drug dissolution and diffusion, without altering the structural properties of the release membrane. Collectively, these findings provide mechanistic insight into ultrasound-responsive reservoir implants and support their potential application in managing chronic conditions, where controllable, on-demand drug release is highly desirable.
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Lu et al. (2026) studied this question.
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