July 1, 1989Circulation
Exercise-induced ST depression in the diagnosis of coronary artery disease. A meta-analysis.
Why the study?
What is the diagnostic accuracy of exercise-induced ST depression compared to coronary angiography for diagnosing coronary artery disease?
Population
24,074 patients across 147 published reports who underwent both exercise electrocardiogram and coronary…
Comparison
Exercise electrocardiogram vs Coronary angiography
Design
Meta-analysis
Authors
Discussion
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Member takes
Implication
Variable exercise ECG accuracy warrants diagnostic caution in CAD; leaves standardization needs and alternatives open for study.
Structured PICO
What is the diagnostic accuracy of exercise-induced ST depression compared to coronary angiography for diagnosing coronary artery disease?
P
Population
24,074 patients across 147 published reports who underwent both exercise electrocardiogram and coronary angiography
I
Intervention
Exercise electrocardiogram (exercise-induced ST depression)
C
Comparator
Coronary angiography
O
Outcome
Diagnostic accuracy (sensitivity and specificity)
There is wide, largely unexplained variability in the reported diagnostic accuracy of the exercise electrocardiogram for coronary artery disease.
Cite This Study
Gianrossi et al. (1989) studied this question.