Why the study?
Studies suggested AIx and PWV increase linearly with age, but pulse pressure data suggest large artery stiffening predominantly occurs later in life.
Population
4,001 healthy, normotensive individuals aged 18 to 90 years
Comparison
Age-related vascular changes in individuals <50 years vs >50 years
Authors
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Age may guide selection of AIx versus PWV for clinical vascular assessment; leaves open their relative prognostic value across age groups in outcome trials.**[[1]](https://www.jacc.org/doi/10.1016/j.jacc.2005.07.037)[[2]](https://www.sciencedirect.
Augmentation index may be a more sensitive marker of arterial stiffening in younger individuals (<50 years), whereas aortic pulse wave velocity is a better measure in older individuals (>50 years).
McEniery et al. (2005) studied this question.
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