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This work examines molecular chirality as a measurable parameter for life's transition.

May 6, 20260 citationsOpen Access

Chirality as the First Order Parameter of Life: The Φ-Stable Transition and Experimental Anchors

Key Points

This work examines molecular chirality as a measurable parameter for life's transition.
Identified chirality using the formula χ = (n_D−n_L)/(n_D+n_L)
Analyzed transitions through Φ-stable theory
Considered energy flux thresholds for different phases of life.
Established chiral non-life and Φ-stable life phases defined by energy flux
Showed that homochirality lowers energy thresholds for life
Presented five falsifiable predictions related to chirality and life transitions.

Abstract

This work identifies molecular chirality (χ = (nD−nL) / (nD+nL) ) as the first measurable order parameter for the transition from non-life to life. Building on Φ-stable theory, χ undergoes a supercritical pitchfork bifurcation at critical energy flux J_χ, defining three phases: racemic chemistry (JJₗifeᶜrit). Homochirality lowers the energy threshold for life. Anchored in QT45 ribozyme, CISS assemblies, supramolecular structures, and heterochiral membranes. Five falsifiable predictions included. Companion to A Theory of Life: The Φ-Stable Transition in Chemical State Space - Puodzius (2026).

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