Background: Non-Rheumatic Valvular Heart Disease (NRVHD) is the 5 th leading cause of death amongst all cardiovascular disease in organization for economic cooperation and development (OECD) countries. Method: Using GBD 2021 meta-tool, we estimated incidence, prevalence, deaths, disability-adjusted life years (DALYs) due to NRVHD by age, sex, year and location across the 38 OECD countries from 1990-2021. Result: From 1990-2021, the average annual percentage change (AAPC) in the age-standardized incidence rate (ASIR) per 100,000 rose by 55%, and prevalence rate (ASPR) increased by 54%. Conversely, the mortality rate (ASMR) fell by 45%, and DALYs rate (ASDALR) decreased by 87%. Nationally, from 1990-2021, the highest AAPC in ASIR observed in Estonia increasing by 2.43% and Portugal by 2.25%, while the US saw a more modest rise of 0.5%. The ASMR increased most notably in Poland by 5.51%, followed by Lithuania at 4.57%, Czechia at 4.39%, and Latvia at 4.115%. In terms of the ASDALR, Poland experienced a 4.41% increase, Lithuania 3.18%, and Latvia 3.08%. From 1990-2021, ASIR rose by 47% for males and 58% for females; ASMR decreased by 43% and 48%, respectively; ASDALR fell by 82% for and 90% respectively, indicating a more pronounced decline in female disease burden. Conclusion: There was a significant increase in the incidence and prevalence rates of NRVHD, indicating growing healthcare challenges. However, reductions in mortality and DALY rates suggest improvements in medical treatments and prevention strategies.
Kaur et al. (Tue,) studied this question.