Key result
Gut microbiota and metabolite panel improves incident hypertension prediction, raising AUC to 0.84.
Population
1,265 hypertension-free adults from the Hispanic Community Health Study/Study of Latinos, mean age 53 years…
Design
Cohort
Follow-up
median of 7 yrs
Authors
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Specific gut bacterial species and circulating metabolites are associated with incident hypertension and can significantly improve risk prediction beyond conventional risk factors.
Cohort (n=1,265)
Specific gut bacterial species and circulating metabolites are associated with incident hypertension and can significantly improve risk prediction beyond conventional risk factors.
Luo et al. (2026) conducted a cohort in Incident hypertension (n=1,265). Gut microbiome and blood metabolome was evaluated on incident HTN. A combined panel of gut microbiota and metabolites significantly improved incident hypertension risk prediction beyond conventional risk factors (AUC improved from 0.77 to 0.84, p<0.001).
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