Retrospective analysis reveals sex-based differences in antimicrobial resistance among uropathogens, indicating a need for tailored antibiotic strategies.
Key Points
Evaluate sex-based differences in uropathogen distribution and antimicrobial resistance among Romanian patients.
Retrospective descriptive analysis
Included 2567 positive urine cultures
Sample collected from 2 urology centers in Bucharest over 1 year
Urine tests with ≥105 CFU/mL and monomicrobial growth were included
Escherichia coli was the most common pathogen, especially in females (54.08%)
Higher resistance rates observed in males for antibiotics like amoxicillin-clavulanic acid (50.37%)
Carbapenem resistance in Klebsiella exceeded 30% in males
Greater male prevalence of Klebsiella and Pseudomonas
Gram-positive bacteria showed stable resistance patterns with sensitivity to linezolid and vancomycin.