Abstract Aim: The aim of this study was to evaluate the outcome and safety of slow-coagulation transscleral cyclophotocoagulation (TSCPC) in patients with uncontrolled glaucoma. Materials and Methods: This was a retrospective study of 58 eyes that underwent TSCPC using slow-coagulation settings at a tertiary hospital. Results: The mean age was 53.86 years; 62.1% were males. The indications for the laser included neovascular glaucoma (34.5%), advanced primary open/angle closure glaucoma (19%), glaucoma secondary to vitreoretinal surgery (23.8%), or penetrating keratoplasty (23.8%). Statistically significant reduction in intraocular pressure (IOP) from 40.19 to 15.33 mmHg was noted at 6 months. Surgical success was achieved in 82.5% at 6 months. The mean antiglaucoma medications reduced from 3.72 to 2.35 ( P < 0.001). No drop in visual acuity was seen in any patient. Majority of the patients (78.9%) did not develop any complication. Some of the complications were hyphema, anterior chamber inflammation, and scleritis that were transient and conservatively managed. Hypotony was recorded in one patient, and repeat laser was advised in five patients. Conclusion: Encouraging safety and efficacy were demonstrated by a noteworthy decrease in IOP and antiglaucoma medications, with insignificant serious complications.
Menon et al. (2026) studied this question.