What question did this study set out to answer?

This research aims to develop a highly sensitive photoelectrochemical platform for PSA detection using carbon dots.

May 6, 20261 citations

Specific detection against PSA by using emission wavelength of carbon dots modulates TiO2/In2S3-based photoelectrochemical aptasensor.

WLWenbo LiQiqihar University HZHongxu ZhaoQiqihar University HQHaiyan QiQiqihar University

Key Points

This research aims to develop a highly sensitive photoelectrochemical platform for PSA detection using carbon dots.
Utilized carbon dots emission wavelength for the detection of PSA.
Developed TiO2/In2S3-based photoelectrochemical aptasensor.
Evaluated the sensor's performance in clinical diagnostics through spiked serum samples.
Achieved a detection limit of 5.0 pg/mL for PSA.
Demonstrated a linear detection range of 0.002-100 ng/mL.
Showed recovery rates between 96.6-100.4% in serum samples.

Abstract

/R-CDs photoelectrode for PSA detection. The sensor demonstrated a wide linear detection range (0.002-100 ng/mL), an ultralow detection limit (5.0 pg/mL), and excellent selectivity. It also exhibited strong stability and reproducibility, with recovery rates of 96.6-100.4% in spiked serum samples. This study not only presents a highly sensitive PEC platform for clinical diagnostics but also underscores the critical role of emission-wavelength modulation of CDs in the rational design of advanced PEC biosensors.

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