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May 6, 2026Circulation

Nighttime Light Exposure Impacts Cardiovascular Disease and Imaging Outcomes

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Key result

Nighttime light exposure >3 lux linked to ~24% higher MI risk.

  • HR 1.24
  • 95% CI 1.07-1.44
  • n=73,286

Why the study?

Does greater nighttime light exposure increase the risk of incident cardiovascular disease and adverse cardiovascular imaging phenotypes in adults?

Population

73,286 adults in the UK Biobank who wore a wrist accelerometer with a light sensor for 7 days between…

Comparison

Nighttime light exposure >3 lux vs No nighttime light exposure >3 lux

Design

Cohort

Follow-up

to 2022 for incident CVD, to 2024 for CVD mortality

Authors

JDJin DaiTulane UniversityWDWen DaiTulane UniversityYHYoriko HeianzaGeneral / Preventive / Lipids

Discussion

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Implication

Objectively measured nighttime light exposure is associated with an increased risk of incident cardiovascular disease and adverse cardiac remodeling, suggesting that maintaining dark nights may promote cardiovascular health.

Key Points

  • This research evaluates the impact of nighttime light exposure on cardiovascular disease risks and imaging phenotypes.
  • Conducted a prospective cohort study of 73,286 adults from the UK Biobank
  • Participants wore wrist accelerometers with light sensors for 7 days to measure light exposure
  • Incident cardiovascular conditions were tracked through hospital admissions and death registries
  • Increased nighttime light exposure was linked to higher risks of myocardial infarction, stroke, and heart failure
  • Greater light exposure associated with adverse cardiac imaging phenotypes
  • Daytime light exposure showed no significant relationship with cardiovascular disease risks

Study Design

Type

Cohort (n=73,286)

Structured PICO

Does greater nighttime light exposure increase the risk of incident cardiovascular disease and adverse cardiovascular imaging phenotypes in adults?

P
Population
73,286 adults in the UK Biobank who wore a wrist accelerometer with a light sensor for 7 days, followed for incident cardiovascular disease to 2022 and cardiovascular mortality to 2024.
E
Exposure
Nighttime light exposure >3 lux
C
Comparator
No nighttime light exposure >3 lux
O
Outcome
Incident myocardial infarction, stroke, heart failure, atrial fibrillation, and cardiovascular disease mortalityhard clinical

Main Result

Hazard Ratio: 1.24 (95% CI 1.07–1.44)

Objectively measured nighttime light exposure is associated with an increased risk of incident cardiovascular disease and adverse cardiac remodeling, suggesting that maintaining dark nights may promote cardiovascular health.

Cite This Study

Dai et al. (2026) reported a cohort. Nighttime light exposure >3 lux vs. None (no nighttime light exposure >3 lux) was evaluated on Incident myocardial infarction (HR 1.24, 95% CI 1.07-1.44). Greater nighttime light exposure (>3 lux) was associated with higher risk of myocardial infarction (HR 1.24; 95% CI 1.07-1.44), stroke, heart failure, atrial fibrillation, and CVD mortality.

synapsesocial.com/papers/69fa8eac04f884e66b531067https://doi.org/10.1161/cir.153.suppl_1.38
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nighttime light exposure and cardiac structure and function2026 · 1 citations
  2. 2Objectively Measured Individual-Level Daytime Versus Nighttime Light Exposure and Cardiovascular Disease Mortality in U.S. Adults2026 · 1 citations
  3. 30085 Associations Between Light Exposure and Cognitive Performance in the Multi-Ethnic Study of Atherosclerosis2026
  4. 4Abstract 27: Chronotype, Life’s Essential 8, and Risk of Cardiovascular Disease: A Prospective Cohort Study in UK Biobank2024 · 2 citations
  5. 5Association between long-term exposure to artificial light at night and air pollution, and cardiovascular diseases in middle-aged and older adults2026