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May 6, 2026Journal of Functional BiomaterialsOpen Access

Biomimetic Deposition of Zn-Doped Calcium Phosphate Coatings on Surface-Activated Ti6Al4V for Multifunctional Implant Interfaces

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Authors

YMYaimi Martin-SantanaYGYadira González-CarranzaLDLeonel Díaz-Tato

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Overview

Biomimetic coatings improve bioactivity and reduce bacterial viability in implants, indicating a multifunctional surface benefit.

Key Points

  • This research investigates the development of multifunctional coatings for titanium implants to improve bone integration and limit bacterial colonization.
  • Fabrication of zinc-doped calcium phosphate coatings on Ti6Al4V using surface activation and supersaturated simulated body fluid.
  • Application of acid and alkali treatments to create a porous, calcium-rich interface for uniform apatite-like layer formation.
  • Analyses including spectroscopic and structural assessments to evaluate Zn incorporation and coating properties.
  • Successful incorporation of Zn without suppressing calcium phosphate phase formation.
  • Demonstrated controlled ionic release and favorable cytocompatibility at moderate Zn levels.
  • Significant reduction in bacterial viability against Streptococcus mutans, attributed to Zn presence.

Cite This Study

Martin-Santana et al. (2026) studied this question.

synapsesocial.com/papers/69fa8eac04f884e66b531098https://doi.org/10.3390/jfb17050225
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Influence of the Etching Time of Ti6Al4V Titanium Alloy with Selected Acid Solutions on Changes in Physical Parameters of the Element2024
  2. 2Multifunctional Titanium Surfaces for Orthopedic Implants: Antimicrobial Activity and Enhanced Osseointegration2021 · 38 citations
  3. 3Assessing the Kinetics and Pore‐Scale Characteristics of Biological Calcium Carbonate Precipitation in Porous Media using a Microfluidic Chip Experiment2020 · 109 citations
  4. 4Biomineralization Process in Three-Dimensional Scaffolds Based on Bacterial Nanocellulose for Bone Tissue Engineering: Chemi-Cal and Morphological Features, and Stem Cell Differentiation2023 · 6 citations