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May 6, 2026Circulation

Abstract WE519: Association between Dynapenic Obesity and Cardiovascular Outcomes and Mortality: A Systematic Review and Meta-analysis

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Authors

DPDarsh PatelSYSai Goutham Reddy YarthaSPSanskar Patel

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Overview

Systematic review demonstrates dynapenic obesity increases cardiovascular events and mortality risk, suggesting it must be considered in risk assessment.

Key Points

  • This research aims to analyze the impact of dynapenic obesity on cardiovascular outcomes and mortality.
  • Conducted a systematic review and meta-analysis
  • Included observational cohort studies reporting adjusted effect sizes
  • Analyzed data on cardiovascular events and mortality related to dynapenic obesity
  • Calculated pooled odds ratios and confidence intervals using random-effects meta-analysis
  • Five studies with over 45,000 participants showed a significant association between dynapenic obesity and cardiovascular events (pooled OR: 1.42)
  • A significant association with cardiovascular mortality (pooled OR: 1.52) was also found
  • Higher incident heart disease risk was noted in women compared to men
  • Dynapenic obesity was identified as a stronger cardiometabolic risk marker than obesity alone

Cite This Study

Patel et al. (2026) studied this question.

synapsesocial.com/papers/69fa980604f884e66b531d59https://doi.org/10.1161/cir.153.suppl_1.we519
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dynapenic abdominal obesity and the risk of cardiovascular diseases: findings from the China Health and Retirement Longitudinal Study2025
  2. 2Gender differences in the relationship between dynapenic abdominal obesity and non-neoplastic digestive system diseases among middle-aged and older adults2026
  3. 3Dynapenic Abdominal Obesity and the Risk of Non-Neoplastic Digestive System Diseases in Postmenopausal Women: A Prospective Cohort Study2026
  4. 4Dynapenic Abdominal Obesity and the Risk of Stroke in Postmenopausal Women2026
  5. 5Dynapenic Abdominal Obesity and Cognitive Impairment in Type 2 Diabetic Patients: A Single‐Center Cross‐Sectional Study2026