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May 6, 2026The Journal of The Korean Dental Association0 citations

Understanding and clinical application of remimazolam in dental treatment for patients with special needs: A literature review

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KKK Y Kim

Key Points

  • To explore the role of remimazolam as a sedative in dental treatment for patients with special needs.
  • Literature review on the use of remimazolam in dental sedation for patients with intellectual disabilities, autism, and cerebral palsy.
  • Evaluation of sedation benefits in managing dental fear and treatment delivery.
  • Remimazolam is effective for sedation in patients with intellectual disability and autism spectrum disorder.
  • Patients report reduced dental fear during procedures with remimazolam compared to traditional methods.
  • Remimazolam provides a bridge between sedation and general anesthesia for difficult cases.

Abstract

Patients with intellectual disability, autism spectrum disorder, cerebral palsy, or severe dental fear often have difficulty undergoing routine outpatient dental treatment, leading to repeated delays or treatment failure. In such cases, sedation may serve as an important option bridging general anesthesia and routine outpatient care. Remimazolam is a recently introduced sedative and general anesthetic agent approved in major regions. This article reviews the clinical significance of remimazolam in dental treatment for patients with disabilities and summarizes the rationale for considering it as an agent for dental sedation.

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Cite This Study

K Y Kim (2026) studied this question.

synapsesocial.com/papers/69fa986a04f884e66b532178https://doi.org/10.22974/jkda.2026.64.4.005
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sedation outcomes for remimazolam, a new benzodiazepine2021 · 104 citations
  2. 2Remimazolam: An Updated Review of a New Sedative and Anaesthetic2022 · 209 citations
  3. 3Safety, pharmacokinetic and pharmacodynamic properties of single ascending dose and continuous infusion of remimazolam besylate in healthy Chinese volunteers2019 · 132 citations
  4. 4A Phase Ib, Dose-Finding Study of Multiple Doses of Remimazolam (CNS 7056) in Volunteers Undergoing Colonoscopy2013 · 188 citations
  5. 5Time‐to‐Event Modeling for Remimazolam for the Indication of Induction and Maintenance of General Anesthesia2020 · 89 citations