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May 6, 2026INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGYOpen Access

Role of chemerin and omentin in predicting ovulatory dysfunction in obese women with polycystic ovary syndrome (PCOS)

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Authors

NANoor Najm AbdullahMAManar Abbas AlameriTMThikra Majid Muhammed

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Overview

Case-control study finds insulin resistance linked to metabolic abnormalities in women with polycystic ovary syndrome.

Key Points

  • Evaluate the predictive ability of chemerin and omentin-1 for ovulatory dysfunction in obese women with PCOS.
  • Case-control study conducted with 150 obese and 70 normal weight women with PCOS and 50 healthy controls.
  • Participants aged 18-35 years, not on hormonal therapy; pregnancy and chronic diseases excluded.
  • Hormones and metabolic markers including chemerin and omentin-1 measured via blood samples.
  • Significant metabolic abnormalities seen in obese PCOS women, including low HDL-C and high insulin resistance.
  • Elevated testosterone and altered LH/FSH ratios observed in the obese PCOS group.
  • Chemerin levels increased while omentin-1 levels decreased, correlating with ovulatory dysfunction and insulin resistance.

Cite This Study

Abdullah et al. (2026) studied this question.

synapsesocial.com/papers/69fa986a04f884e66b532259https://doi.org/10.33086/ijmlst.v8i1.7930
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