A Case Report of Parietal Lobe Glioblastoma and Post-Surgical Neurosensory Deficits

Introduction The early diagnosis of malignant glioblastomas depends on the onset of precursory neurological symptoms, including headache and visual disturbances. The parietal lobe is a neuro-center for visual information processing; thus, a proliferating glioblastoma can disrupt the visual pathway circuitry, resulting in visual field defects and disturbances such as hallucinations. Additionally, surgical resection of tumors in the parietal lobe can create neurosensory deficits affecting the patient’s quality of life. Case Report A 76-year-old man presented with complaints of a progressive headache, complex visual hallucinations, and, on examination, evidence of a neurological visual field defect requiring radiology studies. Neuroimaging revealed a right parietal lobe grade IV glioblastoma, and immunohistochemistry detected an isocitrate dehydrogenase wildtype molecular pattern. He underwent the mainstay of surgical treatment for glioblastoma with adjuvant radiation and chemotherapy three days after neuroimaging confirmation. He reported post-surgical integrated sensorimotor symptoms. Conclusion Glioblastoma is a fast-growing, primary brain tumor with a high morbidity rate as migrating tumor cells invade surrounding tissues. Its location in the parietal lobe can disrupt the visual pathway, causing hallucinations and visual field defects. Although visual disturbances from tumor growth may subside after lesion resection, disruption to regional neurons may cause lasting visual, neurosensory, and motor deficits.