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May 6, 2026Scientific Reports0 citationsOpen Access

Malnutrition by the GLIM criterion and reduced HGS are associated with anthropometric indicators in hospitalized patients

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VLVânia Aparecida Leandro-MerhiLMLucas Rosasco MazziniVBV. Barbieri

Key Points

  • Investigate the association of malnutrition and muscle strength with anthropometric indicators in hospitalized patients.
  • Cross-sectional study design
  • Assessment of BMI, HGS, and various anthropometric measures
  • Statistical analyses including Chi-square, Fisher, and Mann-Whitney tests
  • Logistic regression analysis for associations
  • Malnutrition and reduced HGS significantly correlated with lower calf circumference (CC < 31 cm)
  • Age, HGS, and the GLIM criterion were associated with low body weight defined by BMI
  • Stronger muscle strength linked to a higher chance of better BMI outcomes

Abstract

In the hospital environment, anthropometry is commonly used to assess nutritional status. To assess whether muscle strength and malnutrition, as defined by the GLIM (global leadership initiative on malnutrition) criteria, are associated with anthropometric indicators in hospitalized patients. In a cross-sectional study, body mass index (BMI), mid-upper arm circumference (MUAC), triceps skinfold thickness (TSF), arm muscle circumference (AMC), calf circumference (CC), body weight loss, HGS, and GLIM criteria were investigated. The Chi-square, Fisher, and Mann-Whitney tests were used for comparisons, and the Kappa coefficient for agreement analyses. Univariate and multivariate logistic regressions were used to investigate the association between the GLIM criterion and FPM and anthropometric indicators. HGS (p = 0.0004, OR = 15.193, 95% CI = 3.397; 67,956) and the GLIM criterion (p = 0.0002, OR = 6,142, 95% CI = 2,352; 16,035) were associated with CC < 31 cm. Age (p = 0.0019, OR = 1.054, 95% CI = 1.020; 1,090), the mean HGS (p = 0.0064, OR = 4,094, 95%CI = 1,487; 11.265), and the GLIM criterion (p = 0.0005, OR = 4.798, 95% CI = 1.994; 11,548) were associated with BMI (a higher chance of low body weight by BMI). Reduced HGS and malnutrition, as defined by the GLIM criterion, are associated with CC. Age, HGS, and the GLIM criterion are associated with low body weight, as measured by BMI. These findings reinforce the relevance of using these tools for nutritional care in the hospital setting.

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Cite This Study

Leandro-Merhi et al. (2026) studied this question.

synapsesocial.com/papers/69fa98bd04f884e66b53267bhttps://doi.org/10.1038/s41598-026-50959-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Global Leadership Initiative on Malnutrition criteria using calf and upper arm circumference as phenotypic criteria for assessing muscle mass demonstrate satisfactory validity for diagnosing malnutrition in hospitalized patients: A prospective cohort study2024 · 10 citations
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  4. 4Reduced muscle mass is an important part of Global Leadership Initiative on Malnutrition criteria in nutritional diagnosis of hepatocellular carcinoma2024
  5. 5Association between GLIM diagnosed malnutrition and 18‐month mortality in hospitalized adults with congestive heart failure: A prospective cohort study2025