Research uncovers ADP-ribosylation's impact on DNA and post-translational modification, indicating potential physiological significance.
-dependent modifications of DNA and RNA in mammalian and bacterial cells, including terminal and nucleobase-linked ADP-ribosylation and NAD capping, and discuss outstanding questions regarding their physiological functions and interplay with protein post-translational modification and other nucleic acid modifications.
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Sin et al. (2026) studied this question.
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