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May 6, 2026Journal of Drug Research in Ayurvedic SciencesOpen Access

Ocular safety of Katakaphaladi Anjana through acute eye irritation test in New Zealand white rabbits

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Authors

SSShikha SharmaTATripathi AnkurBNBavalatti Narayan

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Overview

Acute eye irritation tests show Katakaphaladi Anjana is safe for myopia treatment, suggesting no eye irritation occurs.

Key Points

  • This research aims to evaluate the ocular safety of Katakaphaladi Anjana in a rabbit model for visual disturbances.
  • Administered 0.1 g of Katakaphaladi Anjana in right eye of three rabbits
  • Followed OECD-405 guidelines for acute eye irritation testing
  • Conducted observations at 1, 24, 48, and 72 hours
  • Used fluorescein strip to assess ocular damage and ophthalmoscope for epithelial cell examination
  • KPA did not produce any ocular irritant effect
  • KPA is considered nonirritant and safe for ocular use
  • KPA is suggested for administering in myopia without irritation or corrosive effects

Cite This Study

Sharma et al. (2026) studied this question.

synapsesocial.com/papers/69faa25e04f884e66b532e8dhttps://doi.org/10.4103/jdras.jdras_31_25
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