The Subjective Memory Complaints Questionnaire: a systematic review of psychometric properties, clinical applications, and neurobiological correlates

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Key Points

The aim is to systematically review the psychometric properties, clinical uses, and neurobiological correlates of the Subjective Memory Complaints Questionnaire (SMCQ).
Conducted a systematic review of the SMCQ's properties across multiple languages and countries.
Analyzed its reliability in detecting dementia through self-reports and informant reports.
The SMCQ demonstrates strong psychometric properties, with AUC values of 0.84 for self-reports and 0.92 for informant reports.
It is globally validated in 15 languages, but primarily focused on Korean Alzheimer's disease cohorts.
Limited evidence exists for its effectiveness in non-Alzheimer's dementias.

Systematic review evaluates the psychometric properties of the SMCQ for dementia assessment, suggesting its global reliability.

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Han et al. (2026) studied this question.

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