Effects of a preoperative exercise intervention targeting the non-operated limb in patients scheduled for total knee arthroplasty: a pilot study

[Purpose] This study aimed to investigate the effects of a preoperative exercise intervention program on physical function in patients with knee osteoarthritis (KOA) scheduled for total knee arthroplasty (TKA). [Participants and Methods] Twenty-four patients with KOA scheduled for TKA participated in a preoperative exercise program focusing on non-operated limbs. Physical function was evaluated pre- and post-intervention, including knee extension strength (KES), hip abduction strength (HAS), knee range of motion (ROM), pain during activity and at rest (NRS), and performance measures (CS-30, 40 mFWT). Changes were analyzed for statistical significance, and 95% confidence intervals were compared with previously reported MDC95 values. [Results] Activity-related pain, KES, HAS, knee ROM, and CS-30, and 40 mFWT showed statistically significant changes post-intervention. Changes in activity-related NRS and CS-30 levels exceeded the MDC95. [Conclusion] Knee joint function and physical performance of patients with KOA scheduled for TKA significantly changed after eight weeks of preoperative exercise program. Changes exceeding the MDC95 in activity-related pain and CS-30 suggest that our exercise program may have enhanced preoperative physical function.