Background: Geriatric patients are highly vulnerable to drug-related problems (DRPs) due to age-related changes in pharmacokinetics and pharmacodynamics and the increasing prevalence of chronic diseases requiring complex therapy. DRPs are associated with increased mortality, hospital admissions, healthcare costs, and reduced quality of life. Objectives: To assess the effectiveness of clinical pharmacist-led interventions and conduct a systematic evaluation of the prevalence, characteristics, risk factors, and clinical outcomes of DRPs in geriatric patients. Methods: A systematic review on the prevalence, types, risk factors, clinical outcomes, and/or pharmacist interventions in patients aged 60 and older was carried out. Results: DRPs were highly prevalent, particularly among hospitalized and chronically ill patients, ranging from 4% to 30%, with approximately 82%experiencing at least one DRP. Most issues were related to adverse drug reactions, and 50–97% of DRPs were potentially preventable. Conclusion: DRPs are common among geriatric patients, especially those with comorbidities and polypharmacy. Clinical pharmacist interventions, including medication review, patient education, and clinical involvement, play a key role in reducing DRPs and improving medication safety.
*1J. Bhargavi, 2V. Madhavi, 3K. Dharani, 4C. Mohana Priya (Mon,) studied this question.