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May 6, 2026Protein and Peptide Letters

A Comprehensive Review of the Antimicrobial Peptide CM11: Structure,Biological Properties, and Therapeutic Prospects

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Authors

RKRoya KhalilifarIslamic Azad University North Tehran BranchMLM LotfiBaqiyatallah University of Medical SciencesMMMozafar MohammadiBaqiyatallah University of Medical Sciences

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Overview

Comprehensive review highlights CM11's effectiveness against infections and cancer, indicating potential for new treatments.

Key Points

  • The study aims to evaluate the structure, biological properties, and therapeutic potential of CM11 as an antimicrobial and anticancer agent.
  • Reviewed existing literature on CM11's mechanisms of action, formulations, and therapeutic applications.
  • Discussed preclinical evidence regarding CM11’s efficacy against bacterial infections and cancer cell lines.
  • Explored advancements in delivery systems to enhance the stability and effectiveness of CM11.
  • CM11 shows broad-spectrum antimicrobial and anticancer effects, inducing apoptosis in leukemia and hepatocellular carcinoma cells.
  • Enhanced stability and efficacy when formulated in chitosan-based nanoparticles.
  • Synergistic interactions with standard antibiotics/anticancer agents allow for reduced dosages and minimized toxicity.

Cite This Study

Khalilifar et al. (2026) studied this question.

synapsesocial.com/papers/69fadad703f892aec9b1e8aehttps://doi.org/10.2174/0109298665449691260331114022
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