Biomarkers for Diagnosis and Prediction of Outcomes in Contrast-Induced Nephropathy

BACKGROUND: Serum creatinine is suboptimal as a biomarker in the early diagnosis of contrast-induced nephropathy (CIN). In this study, we investigated a panel of novel biomarkers in the early diagnosis of CIN and in assessing patient outcomes. METHODS: were determined using Luminex and ELISA assays. Outcomes were biomarker diagnostic discrimination performance for CIN and mortality after generation of area under receiver operating characteristic curves (AUROCs). RESULTS: M predicted increased mortality of 40% at baseline and 50% at 24 hours. CONCLUSION: were best for predicting prognosis.