What question did this study set out to answer?

To determine the feasibility of terminating drug-refractory incessant atrial fibrillation by creating linear right atrial lesions with radiofrequency catheter ablation.

December 1, 1994Journal of Cardiovascular Electrophysiology

Successful Catheter Ablation of Atrial Fibrillation

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Why the study?

Does catheter ablation using linear right atrial lesions interrupt incessant atrial fibrillation?

Key Points

To determine the feasibility of terminating drug-refractory incessant atrial fibrillation by creating linear right atrial lesions with radiofrequency catheter ablation.
Treated a 46-year-old male with drug-refractory incessant atrial fibrillation who had previously undergone ablation for common atrial flutter (N=1).
Used a 7-French 14-polar catheter to administer 30 radiofrequency energy applications (10 to 40 W), creating two longitudinal and one transverse connecting linear lesions in the right atrium.
The final radiofrequency application successfully terminated an atrial fibrillation episode that had persisted for 55 minutes.
Sustained atrial fibrillation was no longer inducible despite repeated pacing maneuvers, with no procedural complications.
The patient remained completely free of arrhythmia recurrence without antiarrhythmic medications throughout a 3-month follow-up.

Structured PICO

Does catheter ablation using linear right atrial lesions interrupt incessant atrial fibrillation?

Population

1 46-year-old male patient with incessant episodes of atrial fibrillation, previously successfully ablated for common atrial flutter, refractory to antiarrhythmic drugs including amiodarone.

Intervention

Catheter ablation using linear right atrial lesions created by sequential applications of radiofrequency energy (10 to 40 W) via a 7-French 14-polar catheter.

Outcome

Interruption of atrial fibrillation and freedom from arrhythmias at follow-upsurrogate

Catheter ablation using linear right atrial lesions is feasible for terminating incessant atrial fibrillation in humans.

Limitations

Requires further studies to ascertain efficacy and safety
Requires assessment of different catheter techniques

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Case report indicates right atrial linear lesions can terminate persistent AF; leaves open efficacy, safety, and need for prospective trials.

Cite This Study

Haı̈ssaguerre et al. (1994) studied this question.

synapsesocial.com/papers/69fbd8326c3a0c248625dea2 https://doi.org/10.1111/j.1540-8167.1994.tb01146.x

Topics

Atrial fibrillation Persistent AF management AF ablation outcomes Anticoagulation in AF

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Implication

Case report indicates right atrial linear lesions can terminate persistent AF; leaves open efficacy, safety, and need for prospective trials.

Successful Catheter Ablation of Atrial Fibrillation

Key Points

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Topics

Successful Catheter Ablation of Atrial Fibrillation

Key Points

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider