What type of study is this?

This is a Cross-Sectional Study study.

What question did this study set out to answer?

This study investigates the relationship between cough and sleep quality in patients with idiopathic pulmonary fibrosis receiving antifibrotic therapy.

May 7, 2026Journal of Clinical MedicineOpen Access

Cough Burden and Sleep Quality in Patients with Idiopathic Pulmonary Fibrosis Receiving Antifibrotic Therapy: A Cross-Sectional Study in Türkiye

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Authors

HKHalit KazciMuğla University UTUtku TapanMuğla University OTOzge Oral TapanMuğla University

Discussion

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Implication

Cross-sectional study shows cough burden negatively impacts sleep quality in IPF patients receiving antifibrotic treatment, indicating potential for improved patient-centered outcomes.

Key Points

This study investigates the relationship between cough and sleep quality in patients with idiopathic pulmonary fibrosis receiving antifibrotic therapy.
Cross-sectional analytical study conducted in Türkiye.
Patients diagnosed with idiopathic pulmonary fibrosis receiving either nintedanib or pirfenidone were recruited.
Sleep quality assessed using the Pittsburgh Sleep Quality Index and cough-related quality of life evaluated with the Leicester Cough Questionnaire.
Correlation analyses and multivariable linear regression models identified factors associated with sleep quality.
87.8% of patients exhibited poor sleep quality at baseline (PSQI ≥ 5).
Significant improvement in PSQI scores during antifibrotic therapy (p < 0.001).
Cough-related quality of life improved during treatment (p < 0.001).
LCQ score was independently associated with sleep quality during treatment (β = −0.453, p < 0.001).
No significant differences in PSQI or LCQ outcomes between nintedanib and pirfenidone.

Cite This Study

Kazci et al. (2026) studied this question.

synapsesocial.com/papers/69fbe357164b5133a91a2844 https://doi.org/10.3390/jcm15093521

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Implication

Cross-sectional study shows cough burden negatively impacts sleep quality in IPF patients receiving antifibrotic treatment, indicating potential for improved patient-centered outcomes.

Cough Burden and Sleep Quality in Patients with Idiopathic Pulmonary Fibrosis Receiving Antifibrotic Therapy: A Cross-Sectional Study in Türkiye

Discussion

Member takes

Implication

Key Points

Cite This Study

Cough Burden and Sleep Quality in Patients with Idiopathic Pulmonary Fibrosis Receiving Antifibrotic Therapy: A Cross-Sectional Study in Türkiye

Discussion

Member takes

Implication

Key Points

Cite This Study

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