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May 7, 2026Hematology Transfusion and Cell TherapyOpen Access

Harnessing the power of natural killer cells in Lymphoma immunotherapy: Overcoming challenges and enhancing treatment options

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Authors

ERElham RoshandelMLMaryam Vahdat LasemiMMMaryam Mehravar

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Overview

Observations suggest natural killer cell therapy improves response rates in lymphoma, indicating potential synergy with chemotherapy and immune checkpoint inhibitors.

Key Points

  • The research focuses on enhancing natural killer cell therapy for lymphoma treatment and overcoming associated challenges.
  • Exploration of natural killer cell therapy mechanisms and interventions.
  • Review of allogeneic and autologous natural killer cell infusions and chimeric antigen receptor strategies.
  • Analysis of combination therapies with chemotherapy and immune checkpoint inhibitors.
  • Natural killer cells show rapid antitumor responses in lymphoma patients.
  • Allogeneic natural killer cell transplantation reduces graft-versus-host disease risk and improves response rates.
  • Addressing the tumor microenvironment and cell persistence is crucial for enhancing therapy efficacy.

Cite This Study

Roshandel et al. (2026) studied this question.

synapsesocial.com/papers/69fbe357164b5133a91a2a6ehttps://doi.org/10.1016/j.htct.2026.106352
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