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May 7, 2026Open Forum Infectious DiseasesOpen Access

Renal Outcomes in People With HIV-1 and Renal Impairment Treated With B/F/TAF: Integrated Analysis from Nine Phase 3/3b Clinical Trials

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Authors

FPFrank A PostDWD WohlGLGeoffroy Liegeon

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Overview

Integrated analysis reveals stability in renal function and low toxicity in HIV-1 patients with renal impairment treated with B/F/TAF.

Key Points

  • To assess renal outcomes in people with HIV-1 and renal impairment treated with B/F/TAF.
  • Integrated analysis of data from nine Phase 3/3b clinical trials
  • Inclusion of 1069 individuals with mild to moderate renal impairment
  • Follow-up duration of up to 240 weeks
  • Renal function remained stable during the follow-up period
  • Infrequent renal adverse events were reported
  • Discontinuation due to renal toxicity was rare

Cite This Study

Post et al. (2026) studied this question.

synapsesocial.com/papers/69fbe3ca164b5133a91a320chttps://doi.org/10.1093/ofid/ofag265
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