Observational study highlights the role of radiomics in risk stratification for cirrhosis, suggesting integration of body composition metrics and addressing portal vein thrombosis.
Key Points The use of a fixed HVPG value (2.5 mmHg) for healthy controls may introduce systematic bias, particularly near the 6 mmHg clinical threshold. Excluding patients with portal vein thrombosis—present in 15%–25% of cirrhosis—limits the real‐world applicability of current radiomics models. Integrating non‐invasive parameters endorsed by Baveno VII (e.g., liver/spleen stiffness) and CT‐derived body composition metrics could improve risk stratification.
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Li et al. (2026) studied this question.
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